High resolution proton nuclear magnetic resonance studies of human saliva.

High resolution proton Nuclear Magnetic Resonance (NMR) can be used for multicomponent analysis of low molecular weight compounds in small amounts of intact biological materials and biological fluids. It can provide useful qualitative and quantitative biochemical information without the necessity of any pretreatment such as extraction, separation, or purification. The NMR spectra of serum, plasma, cerebrospinal fluid, or urine are related to the clinical conditions of the subjects, and have already been shown to be diagnostically valuable1-3). In some cases, the NMR spectrum of human saliva can also be useful clinically4,5). However, the signal of the spectrum of human saliva is not assigned in detail and the limitation of this method is not made clear. In thisp aper we present the assignments of saliva NMR spectra by one-dimensional and two-dimensional